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Targeting the Retinoblastoma/E2F repressive complex by CDK4/6 inhibitors amplifies oncolytic potency of an oncolytic adenovirus.
Koch, Jana; Schober, Sebastian J; Hindupur, Sruthi V; Schöning, Caroline; Klein, Florian G; Mantwill, Klaus; Ehrenfeld, Maximilian; Schillinger, Ulrike; Hohnecker, Timmy; Qi, Pan; Steiger, Katja; Aichler, Michaela; Gschwend, Jürgen E; Nawroth, Roman; Holm, Per Sonne.
Afiliación
  • Koch J; Department of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Schober SJ; Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology, Stuttgart, University of Tübingen, Tübingen, Germany.
  • Hindupur SV; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804, Munich, Germany.
  • Schöning C; Department of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Klein FG; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, 80804, Munich, Germany.
  • Mantwill K; Department of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Ehrenfeld M; Department of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Schillinger U; Department of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Hohnecker T; Department of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Qi P; Department of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Steiger K; Department of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Aichler M; Department of Urology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Gschwend JE; Department of Pathology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Nawroth R; Helmholtz Zentrum München, German Research Center for Environmental Health, Research Unit Analytical Pathology, Munich, Germany.
  • Holm PS; Department of Urology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Nat Commun ; 13(1): 4689, 2022 08 10.
Article en En | MEDLINE | ID: mdl-35948546
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Retinoblastoma / Infecciones por Adenoviridae / Neoplasias de la Retina / Virus Oncolíticos / Factores de Transcripción E2F / Viroterapia Oncolítica Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Retinoblastoma / Infecciones por Adenoviridae / Neoplasias de la Retina / Virus Oncolíticos / Factores de Transcripción E2F / Viroterapia Oncolítica Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Alemania