Epoxyeicosatrienoic Acids Inhibit the Activation of Murine Fibroblasts by Blocking the TGF-<i>ß</i>1-Smad2/3 Signaling in a PPAR<i>Î³</i>-Dependent Manner.

Tao, Jia-Hao; Liu, Tian; Zhang, Chen-Yu; Zu, Cheng; Yang, Hui-Hui; Liu, Yu-Biao; Yang, Jin-Tong; Zhou, Yong; Guan, Cha-Xiang

Epoxyeicosatrienoic Acids Inhibit the Activation of Murine Fibroblasts by Blocking the TGF-ß1-Smad2/3 Signaling in a PPARÎ³-Dependent Manner.

Tao, Jia-Hao; Liu, Tian; Zhang, Chen-Yu; Zu, Cheng; Yang, Hui-Hui; Liu, Yu-Biao; Yang, Jin-Tong; Zhou, Yong; Guan, Cha-Xiang.

Afiliación

Tao JH; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Liu T; College of Physiology Education, Chongqing University of Arts and Science, Chongqing 412160, China.
Zhang CY; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Zu C; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Yang HH; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Liu YB; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Yang JT; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Zhou Y; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.
Guan CX; Department of Physiology, School of Basic Medicine Science, Central South University, Changsha, Hunan 410078, China.

Oxid Med Cell Longev ; 2022: 7265486, 2022.

Article en En | MEDLINE | ID: mdl-36275905

Asunto(s)

Fibrosis Pulmonar; Factor de Crecimiento Transformador beta1; Animales; Ratones; Ácidos Araquidónicos/farmacología; Bleomicina/efectos adversos; Colágeno/metabolismo; Sistema Enzimático del Citocromo P-450/metabolismo; Epóxido Hidrolasas/metabolismo; Fibroblastos/metabolismo; Células 3T3 NIH; PPAR gamma/metabolismo; Antígeno Nuclear de Célula en Proliferación/metabolismo; Fibrosis Pulmonar/patología; Factor de Crecimiento Transformador beta1/metabolismo

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fibrosis Pulmonar / Factor de Crecimiento Transformador beta1 Límite: Animals Idioma: En Revista: Oxid Med Cell Longev Asunto de la revista: METABOLISMO Año: 2022 Tipo del documento: Article País de afiliación: China

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