Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.

Xia, Yu; Lu, Yun Wei; Hao, Ren Juan; Yu, Gu Ran

Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.

Xia, Yu; Lu, Yun Wei; Hao, Ren Juan; Yu, Gu Ran.

Afiliación

Xia Y; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Lu YW; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Hao RJ; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Yu GR; Department of Neurology, Jiangsu Province Hospital of Chinese Medicine, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

Pharm Biol ; 60(1): 2210-2218, 2022 Dec.

Article en En | MEDLINE | ID: mdl-36369944

Asunto(s)

Barrera Hematoencefálica; Células Endoteliales; Animales; Ratones; Barrera Hematoencefálica/metabolismo; Angiotensina II/toxicidad; FN-kappa B/metabolismo; Receptor Toll-Like 4/metabolismo; Lipopolisacáridos/toxicidad; Factor 88 de Diferenciación Mieloide; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Hypertension; bEnd.3; cerebral small vessel disease; inflammation; transcytosis

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Barrera Hematoencefálica / Células Endoteliales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Pharm Biol Año: 2022 Tipo del documento: Article País de afiliación: China

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