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The PI3K inhibitor pictilisib and the multikinase inhibitors pazopanib and sorafenib have an impact on Rac1 level and migration of medulloblastoma in vitro.
Schoen, Leonie F; Craveiro, Rogerio B; Pietsch, Torsten; Moritz, Thomas; Troeger, Anja; Jordans, Silvia; Dilloo, Dagmar.
Afiliación
  • Schoen LF; Department of Pediatric Hematology and Oncology, Center for Pediatrics, University Hospital Bonn, Bonn, Germany.
  • Craveiro RB; Department of Orthodontics, University Hospital RWTH Aachen, Aachen, Germany.
  • Pietsch T; Department of Neuropathology, University Hospital Bonn, Bonn, Germany.
  • Moritz T; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
  • Troeger A; Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, University Hospital Regensburg, Regensburg, Germany.
  • Jordans S; Department of Pediatric Hematology and Oncology, Center for Pediatrics, University Hospital Bonn, Bonn, Germany.
  • Dilloo D; Department of Pediatric Hematology and Oncology, Center for Pediatrics, University Hospital Bonn, Bonn, Germany.
J Cell Mol Med ; 26(23): 5832-5845, 2022 12.
Article en En | MEDLINE | ID: mdl-36377725
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Proteína de Unión al GTP rac1 / Meduloblastoma Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Proteína de Unión al GTP rac1 / Meduloblastoma Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: Alemania