Analgesic tolerance and cross-tolerance to the bifunctional opioid/neuropeptide FF receptors agonist EN-9 and µ-opioid receptor ligands at the supraspinal level in mice.

Han, Zhenglan; Jin, Guofei; Tang, Jiancai; Wang, Hanyan; Guo, Dongmei; Zhang, Jingping

Han, Zhenglan; Jin, Guofei; Tang, Jiancai; Wang, Hanyan; Guo, Dongmei; Zhang, Jingping.

Afiliación

Han Z; Institute of Basic Medicine and Forensic Medicine, North Sichuan Medical College, 55 Dongshun Road, Nanchong 637100, PR China.
Jin G; Nanchong Key Laboratory of Metabolic Drugs and Biological Products, 55 Dongshun Road, Nanchong 637100, PR China.
Tang J; Nanchong Key Laboratory of Metabolic Drugs and Biological Products, 55 Dongshun Road, Nanchong 637100, PR China.
Wang H; Institute of Basic Medicine and Forensic Medicine, North Sichuan Medical College, 55 Dongshun Road, Nanchong 637100, PR China.
Guo D; Institute of Basic Medicine and Forensic Medicine, North Sichuan Medical College, 55 Dongshun Road, Nanchong 637100, PR China.
Zhang J; Institute of Basic Medicine and Forensic Medicine, North Sichuan Medical College, 55 Dongshun Road, Nanchong 637100, PR China. Electronic address: zhangjingping@nsmc.edu.cn.

Neuropeptides ; 97: 102309, 2023 Feb.

Article en En | MEDLINE | ID: mdl-36410163

Asunto(s)

Analgésicos Opioides; Analgésicos; Ratones; Animales; Analgésicos Opioides/farmacología; Encefalina Ala(2)-MeFe(4)-Gli(5); Analgésicos/farmacología; Receptores Opioides mu/metabolismo; Morfina/farmacología

Palabras clave

Antinociception; Chimeric peptide; Cross-tolerance; Neuropeptide FF; Opioid

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Analgésicos / Analgésicos Opioides Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Neuropeptides Año: 2023 Tipo del documento: Article

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