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Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies.
Li, Xihao; Quick, Corbin; Zhou, Hufeng; Gaynor, Sheila M; Liu, Yaowu; Chen, Han; Selvaraj, Margaret Sunitha; Sun, Ryan; Dey, Rounak; Arnett, Donna K; Bielak, Lawrence F; Bis, Joshua C; Blangero, John; Boerwinkle, Eric; Bowden, Donald W; Brody, Jennifer A; Cade, Brian E; Correa, Adolfo; Cupples, L Adrienne; Curran, Joanne E; de Vries, Paul S; Duggirala, Ravindranath; Freedman, Barry I; Göring, Harald H H; Guo, Xiuqing; Haessler, Jeffrey; Kalyani, Rita R; Kooperberg, Charles; Kral, Brian G; Lange, Leslie A; Manichaikul, Ani; Martin, Lisa W; McGarvey, Stephen T; Mitchell, Braxton D; Montasser, May E; Morrison, Alanna C; Naseri, Take; O'Connell, Jeffrey R; Palmer, Nicholette D; Peyser, Patricia A; Psaty, Bruce M; Raffield, Laura M; Redline, Susan; Reiner, Alexander P; Reupena, Muagututi'a Sefuiva; Rice, Kenneth M; Rich, Stephen S; Sitlani, Colleen M; Smith, Jennifer A; Taylor, Kent D.
Afiliación
  • Li X; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Quick C; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Zhou H; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Gaynor SM; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Liu Y; School of Statistics, Southwestern University of Finance and Economics, Chengdu, China.
  • Chen H; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Selvaraj MS; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Sun R; Center for Genomic Medicine and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
  • Dey R; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Arnett DK; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Bielak LF; Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Bis JC; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Blangero J; University of Kentucky, College of Public Health, Lexington, KY, USA.
  • Boerwinkle E; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Bowden DW; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Brody JA; Department of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, The University of Texas Rio Grande Valley, Brownsville, TX, USA.
  • Cade BE; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Correa A; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
  • Cupples LA; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
  • Curran JE; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
  • de Vries PS; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Duggirala R; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
  • Freedman BI; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA.
  • Göring HHH; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
  • Guo X; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
  • Haessler J; Framingham Heart Study, National Heart, Lung, and Blood Institute and Boston University, Framingham, MA, USA.
  • Kalyani RR; Department of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, The University of Texas Rio Grande Valley, Brownsville, TX, USA.
  • Kooperberg C; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Kral BG; Department of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, The University of Texas Rio Grande Valley, Brownsville, TX, USA.
  • Lange LA; Department of Internal Medicine, Nephrology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
  • Manichaikul A; Department of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, The University of Texas Rio Grande Valley, Brownsville, TX, USA.
  • Martin LW; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
  • McGarvey ST; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.
  • Mitchell BD; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Montasser ME; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.
  • Morrison AC; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Naseri T; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • O'Connell JR; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
  • Palmer ND; Division of Cardiology, George Washington School of Medicine and Health Sciences, Washington, DC, USA.
  • Peyser PA; Department of Epidemiology, International Health Institute, Department of Anthropology, Brown University, Providence, RI, USA.
  • Psaty BM; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Raffield LM; Geriatrics Research and Education Clinical Center, Baltimore VA Medical Center, Baltimore, MD, USA.
  • Redline S; Division of Endocrinology, Diabetes, and Nutrition, Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Reiner AP; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Reupena MS; Ministry of Health, Government of Samoa, Apia, Samoa.
  • Rice KM; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Rich SS; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
  • Sitlani CM; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Smith JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Taylor KD; Departments of Epidemiology, University of Washington, Seattle, WA, USA.
Nat Genet ; 55(1): 154-164, 2023 01.
Article en En | MEDLINE | ID: mdl-36564505
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Estudio de Asociación del Genoma Completo / Lípidos Tipo de estudio: Risk_factors_studies / Systematic_reviews Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Estudio de Asociación del Genoma Completo / Lípidos Tipo de estudio: Risk_factors_studies / Systematic_reviews Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos