Etoposide promotes DNA loop trapping and barrier formation by topoisomerase II.

Le, Tung T; Wu, Meiling; Lee, Joyce H; Bhatt, Neti; Inman, James T; Berger, James M; Wang, Michelle D

Le, Tung T; Wu, Meiling; Lee, Joyce H; Bhatt, Neti; Inman, James T; Berger, James M; Wang, Michelle D.

Afiliación

Le TT; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA.
Wu M; Department of Physics and LASSP, Cornell University, Ithaca, NY, USA.
Lee JH; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA.
Bhatt N; Department of Physics and LASSP, Cornell University, Ithaca, NY, USA.
Inman JT; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Berger JM; Department of Physics and LASSP, Cornell University, Ithaca, NY, USA.
Wang MD; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA.

Nat Chem Biol ; 19(5): 641-650, 2023 05.

Article en En | MEDLINE | ID: mdl-36717711

Asunto(s)

ADN-Topoisomerasas de Tipo II; Inhibidores de Topoisomerasa II; Humanos; Etopósido/farmacología; Inhibidores de Topoisomerasa II/farmacología; ADN-Topoisomerasas de Tipo II/genética; ADN

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: ADN-Topoisomerasas de Tipo II / Inhibidores de Topoisomerasa II Límite: Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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