Fungal Aeroallergen Sensitization Patterns among Airway-Allergic Patients in Zagazig, Egypt.
J Fungi (Basel)
; 9(2)2023 Jan 30.
Article
en En
| MEDLINE
| ID: mdl-36836300
ABSTRACT
BACKGROUND:
Airway allergies such as asthma and allergic rhinitis, as well as their comorbidities, are increasing worldwide, causing significant socioeconomic health burdens to societies. It is estimated that between 3% and 10% of the population is allergic to fungi. The type of fungal sensitization varies from one geographical region to another. The present study aimed to identify the common fungal aeroallergen sensitization patterns among airway-allergic patients residing in the Zagazig locality, Egypt, in order to obtain a better understanding of fungal allergy, in addition to improving the awareness and management strategies for those patients.METHODS:
The present cross-sectional study included 200 allergic rhinitis and asthma patients. Sensitization to fungal aeroallergens was evaluated by skin prick testing and in vitro measurement of total and specific immunoglobulin E.RESULTS:
As determined by a skin prick test, 58% of the patients studied were allergic to mixed molds. Alternaria alternata was the predominant fungal aeroallergen among the studied patients (72.2%), which was followed by Aspergillus fumigatus (53.45%), Penicillium notatum (52.6%), Candida albicans (34.5%), and Aspergillus niger (25%).CONCLUSION:
Mixed mold sensitization ranked fourth among the most frequent aeroallergens in airway-allergic patients, and Alternaria alternata was the most frequently encountered fungal aeroallergen in the Zagazig locality.
Texto completo:
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Base de datos:
MEDLINE
Tipo de estudio:
Observational_studies
Idioma:
En
Revista:
J Fungi (Basel)
Año:
2023
Tipo del documento:
Article
País de afiliación:
Egipto