Characteristics and outcomes of patients with gastroparesis using enteral and/or exclusive parenteral nutrition.
JPEN J Parenter Enteral Nutr
; 47(4): 541-549, 2023 05.
Article
en En
| MEDLINE
| ID: mdl-36871132
ABSTRACT
BACKGROUND:
Patients with gastroparesis (Gp) may need enteral nutrition (EN) or exclusive parenteral nutrition (PN). Among patients with Gp, we aimed to (1) identify the frequency of EN and exclusive PN use and (2) explore characteristics of patients using EN and/or exclusive PN compared with those using oral nutrition (ON), including changes over 48 weeks.METHODS:
Patients with Gp underwent history and physical examination, gastric emptying scintigraphy, water load satiety testing (WLST), and questionnaires assessing gastrointestinal symptoms and quality of life (QOL). Patients were observed 48 weeks.RESULTS:
Of 971 patients with Gp (idiopathic, 579; diabetic, 336; post-Nissen fundoplication, 51), 939 (96.7%) were using ON only, 14 (1.4%) using exclusive PN, and 18 (1.9%) using EN. Compared with patients receiving ON, patients receiving exclusive PN and/or EN were younger, had lower body mass index, and had greater symptom severity. Patients receiving exclusive PN and/or EN had lower physical QOL but not mental QOL or Gp-related QOL scores. Patients receiving exclusive PN and/or EN ingested less water during WLST but did not have worse gastric emptying. Of those who had been receiving exclusive PN and/or EN, 50% and 25%, respectively, resumed ON at 48-week follow-up.CONCLUSIONS:
This study describes patients with Gp requiring exclusive PN and/or EN for nutrition support, who represent a small (3.3%) but important subset of patients with Gp. Unique clinical and physiological parameters are associated with this subset and provide insight into the use of nutrition support in Gp.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Gastroparesia
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
JPEN J Parenter Enteral Nutr
Año:
2023
Tipo del documento:
Article
País de afiliación:
Estados Unidos