Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5- <i>a</i> ]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis.

Monti, Ludovica; Liu, Lawrence J; Varricchio, Carmine; Lucero, Bobby; Alle, Thibault; Yang, Wenqian; Bem-Shalom, Ido; Gilson, Michael; Brunden, Kurt R; Brancale, Andrea; Caffrey, Conor R; Ballatore, Carlo

Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5- a ]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis.

Monti, Ludovica; Liu, Lawrence J; Varricchio, Carmine; Lucero, Bobby; Alle, Thibault; Yang, Wenqian; Bem-Shalom, Ido; Gilson, Michael; Brunden, Kurt R; Brancale, Andrea; Caffrey, Conor R; Ballatore, Carlo.

Afiliación

Monti L; Center for Discovery and Innovation in Parasitic Diseases (CDIPD), Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Liu LJ; Present affiliation: Imperial College London, Chemistry Department, Molecular Sciences Research Hub, 82 Wood Lane, London W12 0BZ, UK.
Varricchio C; Center for Discovery and Innovation in Parasitic Diseases (CDIPD), Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Lucero B; Cardiff School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF103NB, U.K.
Alle T; Center for Discovery and Innovation in Parasitic Diseases (CDIPD), Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Yang W; Department of Chemistry & Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Bem-Shalom I; Center for Discovery and Innovation in Parasitic Diseases (CDIPD), Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Gilson M; Center for Discovery and Innovation in Parasitic Diseases (CDIPD), Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Brunden KR; Center for Discovery and Innovation in Parasitic Diseases (CDIPD), Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Brancale A; Center for Discovery and Innovation in Parasitic Diseases (CDIPD), Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093.
Caffrey CR; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA 19104-6323.
Ballatore C; Cardiff School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF103NB, U.K.

bioRxiv ; 2023 Mar 11.

Article en En | MEDLINE | ID: mdl-36945407

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2023 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2023 Tipo del documento: Article