Synthesis of 6â³-Modified Kanamycin A Derivatives and Evaluation of Their Antibacterial Properties.

Shapovalova, Kseniya; Zatonsky, Georgy; Grammatikova, Natalia; Osterman, Ilya; Razumova, Elizaveta; Shchekotikhin, Andrey; Tevyashova, Anna

Synthesis of 6â³-Modified Kanamycin A Derivatives and Evaluation of Their Antibacterial Properties.

Shapovalova, Kseniya; Zatonsky, Georgy; Grammatikova, Natalia; Osterman, Ilya; Razumova, Elizaveta; Shchekotikhin, Andrey; Tevyashova, Anna.

Afiliación

Shapovalova K; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, 119021 Moscow, Russia.
Zatonsky G; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, 119021 Moscow, Russia.
Grammatikova N; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, 119021 Moscow, Russia.
Osterman I; Center of Life Sciences, Skolkovo Institute of Science and Technology, Bolshoy Boulevard 30, bld. 1, 121205 Moscow, Russia.
Razumova E; Center for Translational Medicine, Sirius University of Science and Technology, Olympic Avenue 1, 354340 Sochi, Russia.
Shchekotikhin A; Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Tevyashova A; Gause Institute of New Antibiotics, 11 B. Pirogovskaya, 119021 Moscow, Russia.

Pharmaceutics ; 15(4)2023 Apr 07.

Article en En | MEDLINE | ID: mdl-37111662

Palabras clave

aminoglycosides; antimicrobial resistance; chemical modification; kanamycin; mode of action; translation inhibition

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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Pharmaceutics Año: 2023 Tipo del documento: Article País de afiliación: Rusia

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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Pharmaceutics Año: 2023 Tipo del documento: Article País de afiliación: Rusia