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Targeted hyperactivation of AKT through inhibition of ectopic expressed SHIP1 induces cell death in colon carcinoma cells and derived metastases.
Ehm, Patrick A H; Linnebacher, Michael; Block, Andreas; Rehbach, Christoph; Jücker, Manfred.
Afiliación
  • Ehm PAH; Institute of Biochemistry and Signal Transduction, Center for Experimental Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. Electronic address: p.trickehm@gmail.com.
  • Linnebacher M; Molecular Oncology and Immunotherapy, Clinic of General, Thoracic, Vascular and Transplantation Surgery, University of Rostock, Rostock, Germany.
  • Block A; Department of Oncology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.
  • Rehbach C; Institute of Biochemistry and Signal Transduction, Center for Experimental Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany; MSH Medical School Hamburg, Department of Human Medicine, Hamburg, Germany.
  • Jücker M; Institute of Biochemistry and Signal Transduction, Center for Experimental Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.
Cell Signal ; 108: 110720, 2023 08.
Article en En | MEDLINE | ID: mdl-37207939
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Carcinoma / Neoplasias del Colon / Proteínas Proto-Oncogénicas c-akt / Fosfatidilinositol-3,4,5-Trifosfato 5-Fosfatasas Límite: Humans Idioma: En Revista: Cell Signal Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Carcinoma / Neoplasias del Colon / Proteínas Proto-Oncogénicas c-akt / Fosfatidilinositol-3,4,5-Trifosfato 5-Fosfatasas Límite: Humans Idioma: En Revista: Cell Signal Año: 2023 Tipo del documento: Article