Discovery and pharmacological characterization of novel positive allosteric modulators acting on skeletal muscle-type nicotinic acetylcholine receptors.

Saito, Asako; Matsui, Shigeo; Chino, Ayaka; Sato, Shota; Takeshita, Nobuaki

Saito, Asako; Matsui, Shigeo; Chino, Ayaka; Sato, Shota; Takeshita, Nobuaki.

Afiliación

Saito A; Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba, Ibaraki, 305-8585, Japan. Electronic address: asako.satio@astellas.com.
Matsui S; Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba, Ibaraki, 305-8585, Japan.
Chino A; Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba, Ibaraki, 305-8585, Japan.
Sato S; Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba, Ibaraki, 305-8585, Japan.
Takeshita N; Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba, Ibaraki, 305-8585, Japan.

Biochem Biophys Res Commun ; 668: 27-34, 2023 08 06.

Article en En | MEDLINE | ID: mdl-37235916

Asunto(s)

Receptores Nicotínicos; Ratas; Animales; Humanos; Receptores Nicotínicos/metabolismo; Regulación Alostérica; Agonistas Nicotínicos/farmacología; Transmisión Sináptica; Músculo Esquelético/metabolismo

Palabras clave

Myasthenia gravis; Neuromuscular diseases; Nicotinic acetylcholine receptor; Positive allosteric modulator; Skeletal muscle

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Receptores Nicotínicos Límite: Animals / Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2023 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google