Differential target multiplexed spinal cord stimulator: a review of preclinical/clinical data and hardware advancement.
Pain Manag
; 13(4): 233-242, 2023 Apr.
Article
en En
| MEDLINE
| ID: mdl-37249006
ABSTRACT
Spinal cord stimulation (SCS) is an effective neuromodulation technique for treating chronic neuropathic pain. Recent rapid growth in understanding its mechanism has led to the development of glial cell-based differential target multiplexed (DTM) stimulation and its derivative algorithm. Both preclinical research and clinical trials in humans showed superior pain relief using DTM SCS compared with traditional SCS. Another multicenter prospective clinical trial showed significant pain score reduction and energy saving using the DTM derivative algorithm. This review paper summarizes the evidence related to using DTM stimulation for other painful conditions such as nonsurgical low back pain and upper-limb pain. All these advanced programming options can be delivered using an innovative platform, the Medtronic Intellis™ neurostimulator.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Dolor de la Región Lumbar
/
Dolor Crónico
/
Estimulación de la Médula Espinal
Tipo de estudio:
Clinical_trials
/
Observational_studies
Límite:
Humans
Idioma:
En
Revista:
Pain Manag
Año:
2023
Tipo del documento:
Article
País de afiliación:
Estados Unidos