Targeting transcriptional kinase of CDK7 halts proliferation of multiple myeloma cells by modulating the function of canonical NF-kB pathway and cell cycle regulatory proteins.

Dutta, Rudra Prasad; Kumar, Rohit; Tembhare, Prashant R; Bagal, Bhausaheb; Swain, Rajeeb Kumar; Hasan, Syed Khizer

Dutta, Rudra Prasad; Kumar, Rohit; Tembhare, Prashant R; Bagal, Bhausaheb; Swain, Rajeeb Kumar; Hasan, Syed Khizer.

Afiliación

Dutta RP; Hasan Lab, ACTREC-Tata Memorial Centre, Mumbai, India; Hematology and Medical Oncology, Mount Sinai School of Medicine, New York, NY, USA.
Kumar R; Hasan Lab, ACTREC-Tata Memorial Centre, Mumbai, India; Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Tembhare PR; Hematopathology Laboratory, ACTREC, Tata Memorial Centre, Mumbai, India.
Bagal B; Adult Hematolymphoid Disease Management Group, Department of Medical Oncology, Tata Memorial Centre, Mumbai, India.
Swain RK; Developmental Biology, Institute of Life Sciences, Bhubaneswar, Bhubaneswar, India.
Hasan SK; Hasan Lab, ACTREC-Tata Memorial Centre, Mumbai, India; Homi Bhabha National Institute, Mumbai, India. Electronic address: shasan@actrec.gov.in.

Transl Oncol ; 35: 101729, 2023 Sep.

Article en En | MEDLINE | ID: mdl-37369156

Palabras clave

Bortezomib resistant; Cyclin dependent kinase 7; Multiple myeloma; Nuclear factor kappa B pathway

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Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Transl Oncol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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