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Multidimensional biomarkers for multiple system atrophy: an update and future directions.
Wan, Linlin; Zhu, Sudan; Chen, Zhao; Qiu, Rong; Tang, Beisha; Jiang, Hong.
Afiliación
  • Wan L; Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, China.
  • Zhu S; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, 410008, China.
  • Chen Z; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China.
  • Qiu R; Department of Radiology, Xiangya Hospital, Central South University, Changsha, 410008, China.
  • Tang B; National International Collaborative Research Center for Medical Metabolomics, Central South University, Changsha, 410008, China.
  • Jiang H; Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Transl Neurodegener ; 12(1): 38, 2023 07 28.
Article en En | MEDLINE | ID: mdl-37501056
ABSTRACT
Multiple system atrophy (MSA) is a fatal progressive neurodegenerative disease. Biomarkers are urgently required for MSA to improve the diagnostic and prognostic accuracy in clinic and facilitate the development and monitoring of disease-modifying therapies. In recent years, significant research efforts have been made in exploring multidimensional biomarkers for MSA. However, currently few biomarkers are available in clinic. In this review, we systematically summarize the latest advances in multidimensional biomarkers for MSA, including biomarkers in fluids, tissues and gut microbiota as well as imaging biomarkers. Future directions for exploration of novel biomarkers and promotion of implementation in clinic are also discussed.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Atrofia de Múltiples Sistemas Límite: Humans Idioma: En Revista: Transl Neurodegener Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Atrofia de Múltiples Sistemas Límite: Humans Idioma: En Revista: Transl Neurodegener Año: 2023 Tipo del documento: Article País de afiliación: China