Multidimensional biomarkers for multiple system atrophy: an update and future directions.
Transl Neurodegener
; 12(1): 38, 2023 07 28.
Article
en En
| MEDLINE
| ID: mdl-37501056
ABSTRACT
Multiple system atrophy (MSA) is a fatal progressive neurodegenerative disease. Biomarkers are urgently required for MSA to improve the diagnostic and prognostic accuracy in clinic and facilitate the development and monitoring of disease-modifying therapies. In recent years, significant research efforts have been made in exploring multidimensional biomarkers for MSA. However, currently few biomarkers are available in clinic. In this review, we systematically summarize the latest advances in multidimensional biomarkers for MSA, including biomarkers in fluids, tissues and gut microbiota as well as imaging biomarkers. Future directions for exploration of novel biomarkers and promotion of implementation in clinic are also discussed.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Atrofia de Múltiples Sistemas
Límite:
Humans
Idioma:
En
Revista:
Transl Neurodegener
Año:
2023
Tipo del documento:
Article
País de afiliación:
China