Combination of Immunotherapy and Radiation Therapy in Gastrointestinal Cancers: An Appraisal of the Current Literature and Ongoing Research.
Curr Oncol
; 30(7): 6432-6446, 2023 07 05.
Article
en En
| MEDLINE
| ID: mdl-37504333
ABSTRACT
Oncological outcomes are improving in gastrointestinal cancer with advancements in systemic therapies, and there is notable potential in combining immunotherapy and radiation therapy (RT) to allow for further improvements. Various preclinical and early phase II studies have shown promising synergy with immunotherapy and RT in gastrointestinal cancer. A few recent phase III studies have shown improved survival with the addition of immunotherapy to standard treatment for gastrointestinal cancer. The timing, duration, sequencing, and integration with other anti-cancer treatments are still areas of ongoing research. We have reviewed the published and ongoing studies of the combinations of immunotherapy and RT in gastrointestinal cancers.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Gastrointestinales
Tipo de estudio:
Observational_studies
Límite:
Humans
Idioma:
En
Revista:
Curr Oncol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Estados Unidos