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Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers.
Quintanal-Villalonga, Alvaro; Durani, Vidushi; Sabet, Amin; Redin, Esther; Kawasaki, Kenta; Shafer, Moniquetta; Karthaus, Wouter R; Zaidi, Samir; Zhan, Yingqian A; Manoj, Parvathy; Sridhar, Harsha; Shah, Nisargbhai S; Chow, Andrew; Bhanot, Umesh K; Linkov, Irina; Asher, Marina; Yu, Helena A; Qiu, Juan; de Stanchina, Elisa; Patel, Radhika A; Morrissey, Colm; Haffner, Michael C; Koche, Richard P; Sawyers, Charles L; Rudin, Charles M.
Afiliación
  • Quintanal-Villalonga A; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Durani V; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Sabet A; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY 10065, USA.
  • Redin E; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Kawasaki K; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Shafer M; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Karthaus WR; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Zaidi S; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Zhan YA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Manoj P; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Sridhar H; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Shah NS; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Chow A; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Bhanot UK; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Linkov I; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Asher M; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Yu HA; Weill Cornell Medical College, New York, NY 10065, USA.
  • Qiu J; Precision Pathology Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • de Stanchina E; Precision Pathology Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Patel RA; Precision Pathology Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Morrissey C; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Haffner MC; Weill Cornell Medical College, New York, NY 10065, USA.
  • Koche RP; Antitumor Assessment Core, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Sawyers CL; Antitumor Assessment Core, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Rudin CM; Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Center, Seattle, WA 19024, USA.
Sci Transl Med ; 15(707): eadf7006, 2023 08 02.
Article en En | MEDLINE | ID: mdl-37531417
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Adenocarcinoma / Carcinoma Pulmonar de Células Pequeñas / Factores de Transcripción SOXB1 / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Adenocarcinoma / Carcinoma Pulmonar de Células Pequeñas / Factores de Transcripción SOXB1 / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos