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[Progress in the application of alveolar organoids in common lung diseases].
Kong, W G; Lin, X; Zhu, J H; Lin, Z Q; Zhu, S Y; Zhang, Z L; Lu, W J.
Afiliación
  • Kong WG; The First Affiliated Hospital of Guangzhou Medical University, Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510182, China.
  • Lin X; Guangzhou Medical University, Guangzhou 510182, China.
  • Zhu JH; The First Affiliated Hospital of Guangzhou Medical University, Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510182, China.
  • Lin ZQ; The First Affiliated Hospital of Guangzhou Medical University, Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510182, China.
  • Zhu SY; Guangzhou Medical University, Guangzhou 510182, China.
  • Zhang ZL; The First Affiliated Hospital of Guangzhou Medical University, Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510182, China.
  • Lu WJ; The First Affiliated Hospital of Guangzhou Medical University, Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510182, China.
Zhonghua Jie He He Hu Xi Za Zhi ; 46(8): 829-834, 2023 Aug 12.
Article en Zh | MEDLINE | ID: mdl-37536996
ABSTRACT
Organoids are tissue cultures formed by culturing cells in three-dimensional environments that simulate the physiological or pathological conditions of the human body. The cultivation of organoids is used to study the temporal and spatial transformation of cells during the development of tissues or organs, to investigate changes in cellular functions and inter-communications caused by various risk factors, and to discover potential therapeutic targets. This article provided an overview of the cultivation and identification methods of alveolar organoids, as well as the research progress in their application to common respiratory diseases such as pulmonary fibrosis, chronic obstructive pulmonary disease, viral pneumonia, and so on. The limitations and future applications of alveolar organoids are also analyzed and discussed.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neumonía Viral / Enfermedad Pulmonar Obstructiva Crónica / Enfermedades Pulmonares Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: Zh Revista: Zhonghua Jie He He Hu Xi Za Zhi Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neumonía Viral / Enfermedad Pulmonar Obstructiva Crónica / Enfermedades Pulmonares Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: Zh Revista: Zhonghua Jie He He Hu Xi Za Zhi Año: 2023 Tipo del documento: Article País de afiliación: China