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Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
Sanmarco, Liliana M; Rone, Joseph M; Polonio, Carolina M; Fernandez Lahore, Gonzalo; Giovannoni, Federico; Ferrara, Kylynne; Gutierrez-Vazquez, Cristina; Li, Ning; Sokolovska, Anna; Plasencia, Agustin; Faust Akl, Camilo; Nanda, Payal; Heck, Evelin S; Li, Zhaorong; Lee, Hong-Gyun; Chao, Chun-Cheih; Rejano-Gordillo, Claudia M; Fonseca-Castro, Pedro H; Illouz, Tomer; Linnerbauer, Mathias; Kenison, Jessica E; Barilla, Rocky M; Farrenkopf, Daniel; Stevens, Nikolas A; Piester, Gavin; Chung, Elizabeth N; Dailey, Lucas; Kuchroo, Vijay K; Hava, David; Wheeler, Michael A; Clish, Clary; Nowarski, Roni; Balsa, Eduardo; Lora, Jose M; Quintana, Francisco J.
Afiliación
  • Sanmarco LM; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Rone JM; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Polonio CM; Evergrande Center for Immunologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Fernandez Lahore G; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Giovannoni F; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Ferrara K; Evergrande Center for Immunologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Gutierrez-Vazquez C; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Li N; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Sokolovska A; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Plasencia A; Synlogic Therapeutics, Cambridge, MA, USA.
  • Faust Akl C; Synlogic Therapeutics, Cambridge, MA, USA.
  • Nanda P; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Heck ES; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Li Z; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Lee HG; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Chao CC; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Rejano-Gordillo CM; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Fonseca-Castro PH; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Illouz T; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Linnerbauer M; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Kenison JE; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Barilla RM; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Farrenkopf D; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Stevens NA; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Piester G; Evergrande Center for Immunologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Chung EN; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Dailey L; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Kuchroo VK; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Hava D; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Wheeler MA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Clish C; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Nowarski R; Evergrande Center for Immunologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Balsa E; Synlogic Therapeutics, Cambridge, MA, USA.
  • Lora JM; Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
  • Quintana FJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nature ; 620(7975): 881-889, 2023 Aug.
Article en En | MEDLINE | ID: mdl-37558878
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Células Dendríticas / Sistema Nervioso Central / Ácido Láctico / Subunidad alfa del Factor 1 Inducible por Hipoxia Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nature Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Células Dendríticas / Sistema Nervioso Central / Ácido Láctico / Subunidad alfa del Factor 1 Inducible por Hipoxia Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nature Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos