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Ginsenosides in endometrium-related diseases: Emerging roles and mechanisms.
Zhang, Yang-Yang; Li, Mao-Zhi; Shen, Hui-Hui; Abudukeyoumu, Ayitila; Xie, Feng; Ye, Jiang-Feng; Xu, Feng-Yuan; Sun, Jian-Song; Li, Ming-Qing.
Afiliación
  • Zhang YY; Institute of Obstetrics and Gynecology, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai 200080, People's Republic of China; Shanghai Medical College, Fudan University, Shanghai 200032, People's Republic of China.
  • Li MZ; Institute of Obstetrics and Gynecology, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai 200080, People's Republic of China; Shanghai Medical College, Fudan University, Shanghai 200032, People's Republic of China.
  • Shen HH; Institute of Obstetrics and Gynecology, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai 200080, People's Republic of China.
  • Abudukeyoumu A; Department of Gynecology, Shanghai Jiading Maternal Child Health Hospital, Shanghai 201800, People's Republic of China.
  • Xie F; Medical Center of Diagnosis and Treatment for Cervical and Intrauterine Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, People's Republic of China.
  • Ye JF; Institute for Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore 138632, Singapore.
  • Xu FY; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Sun JS; School of Life Science and Health Engineering, Jiangnan University, Wuxi 214122, People's Republic of China.
  • Li MQ; Institute of Obstetrics and Gynecology, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai 200080, People's Republic of China; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai 200080, People's
Biomed Pharmacother ; 166: 115340, 2023 Oct.
Article en En | MEDLINE | ID: mdl-37625321
Ginsenosides, agents extracted from an important herb (ginseng), are expected to provide new therapies for endometrium-related diseases. Based on the molecular types of ginsenosides, we reviewed the main pharmacological effects of ginsenosides against endometrium-related diseases (e.g., endometrial cancers, endometriosis, and endometritis). The mechanism of action of ginsenosides involves inducing apoptosis of endometrium-related cells, promoting autophagy of endometrium-related cells, regulating epithelial-mesenchymal transition (EMT) in endometrium-related cells, and activating the immune system to kill cells associated with endometrial diseases. We hope to provide a theoretical foundation for the treatment of endometrium-related diseases by ginsenosides.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Enfermedades Uterinas / Neoplasias Endometriales / Ginsenósidos / Endometriosis Límite: Female / Humans Idioma: En Revista: Biomed Pharmacother Año: 2023 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Enfermedades Uterinas / Neoplasias Endometriales / Ginsenósidos / Endometriosis Límite: Female / Humans Idioma: En Revista: Biomed Pharmacother Año: 2023 Tipo del documento: Article