Case Report: Clinical analysis of a cluster outbreak of chlamydia psittaci pneumonia.
Front Cell Infect Microbiol
; 13: 1214297, 2023.
Article
en En
| MEDLINE
| ID: mdl-37637462
ABSTRACT
Objective:
To explore the clinical characteristics and prognosis of clustered cases of psittacosis pneumonia.Method:
We retrospectively analyzed the clinical data of a cluster outbreak of psittacosis pneumonia. The analysis included epidemiological data, clinical symptoms, laboratory results, and prognosis. The diagnosis was made using mNGS and nested PCR technology.Result:
Of the four cases, two had direct contact with diseased poultry while the other two did not. All cases presented with more than 39.5 °C fever and chills. Additionally, significant increases in C-reactive protein, ferritin, creatine kinase, and lactate dehydrogenase were observed in all cases, while absolute lymphocyte count decreased. Case 2 also had increased calcitonin levels. Acute respiratory failure occurred during the treatment of case 1 and case 2, leading to tracheal intubation and ventilator-assisted ventilation. Unfortunately, case 2 passed away due to sepsis and multiple organ dysfunction, while the other cases had a positive prognosis.Conclusion:
mNGS facilitated the early diagnosis of psittacosis pneumonia. It is important to note that there is still a substantial risk of human-to-human transmission in psittacosis pneumonia. Absolute lymphocyte count and calcitonin levels can predict the severity and prognosis of the disease.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Psitacosis
/
Neumonía
/
Chlamydophila psittaci
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Humans
Idioma:
En
Revista:
Front Cell Infect Microbiol
Año:
2023
Tipo del documento:
Article
País de afiliación:
China