Etoricoxib nanostructured lipid carriers attenuate inflammation by modulating Cyclooxygenase-2 signaling and activation of nuclear factor-&#954;B-p65 pathways in radiation-induced acute cardiotoxicity in rats.

Taha, Eman Fs; Hamed, Noha Sayed; Khateeb, Sahar

Etoricoxib nanostructured lipid carriers attenuate inflammation by modulating Cyclooxygenase-2 signaling and activation of nuclear factor-κB-p65 pathways in radiation-induced acute cardiotoxicity in rats.

Taha, Eman Fs; Hamed, Noha Sayed; Khateeb, Sahar.

Afiliación

Taha EF; Health Radiation Research Department, National Centre for Radiation Research and Technology, Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt.
Hamed NS; Radioisotopes Department, Nuclear Research Centre, Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt.
Khateeb S; Biochemistry Division, Department of Chemistry, Faculty of Science, Fayoum University, Fayoum, Egypt. Electronic address: sms07@fayoum.edu.eg.

Eur J Pharmacol ; 957: 176029, 2023 Oct 15.

Article en En | MEDLINE | ID: mdl-37648012

Asunto(s)

Cardiotoxicidad; FN-kappa B; Humanos; Animales; Ratas; Ciclooxigenasa 2; Cardiotoxicidad/etiología; Cardiotoxicidad/prevención & control; Etoricoxib/farmacología; Inflamación/tratamiento farmacológico; Lípidos

Palabras clave

Antioxidant activity; Etoricoxib; Gamma radiation; Inflammation; Nanostructured lipid carriers

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: FN-kappa B / Cardiotoxicidad Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Revista: Eur J Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: Egipto

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