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Design, synthesis and bioevaluation of PI3Kα-selective inhibitors as potential colorectal cancer drugs.
Zheng, Xue-Mei; Chen, Yuan-Si; Ban, Yu-Juan; Wang, Yu-Jie; Dong, Yong-Xi; Lei, Li; Guo, Bing; Wang, Jian-Ta; Tang, Lei; Li, Hong-Liang; Zhang, Ji-Quan.
Afiliación
  • Zheng XM; Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, College of Pharmacy, Guizhou Medical University, Guiyang, 550025, China.
  • Chen YS; School of Medicine, Yunnan University, 2 Cuihu North Road, Kunming, 650091, China.
  • Ban YJ; Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, College of Pharmacy, Guizhou Medical University, Guiyang, 550025, China.
  • Wang YJ; Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, College of Pharmacy, Guizhou Medical University, Guiyang, 550025, China.
  • Dong YX; Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, College of Pharmacy, Guizhou Medical University, Guiyang, 550025, China.
  • Lei L; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, College of Basic Medicine, Guizhou Medical University, Guiyang, 550025, China.
  • Guo B; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, College of Basic Medicine, Guizhou Medical University, Guiyang, 550025, China.
  • Wang JT; Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, College of Pharmacy, Guizhou Medical University, Guiyang, 550025, China.
  • Tang L; Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, College of Pharmacy, Guizhou Medical University, Guiyang, 550025, China. Electronic address: tlei1974@163.com.
  • Li HL; School of Medicine, Yunnan University, 2 Cuihu North Road, Kunming, 650091, China. Electronic address: lihongliang@ynu.edu.cn.
  • Zhang JQ; Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, College of Pharmacy, Guizhou Medical University, Guiyang, 550025, China. Electronic address: zjqgmc@163.com.
Eur J Med Chem ; 260: 115754, 2023 Nov 15.
Article en En | MEDLINE | ID: mdl-37651880
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Fosfatidilinositol 3-Quinasas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Fosfatidilinositol 3-Quinasas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article País de afiliación: China