Ca2+ signaling in plant manganese uptake: CPK21/23 kinases phosphorylate and activate manganese transporter NRAMP1.

ABSTRACT

This brief article highlights the results of Fu et al. (Proc Natl Acad Sci USA 119e2204574119, 2022), who recently found that manganese (Mn) deficiency triggers long-lasting multicellular Ca2+ oscillations in the elongation zone (EZ) of Arabidopsis roots and revealed a Ca2+-CPK21/23-NRAMP1 axis as an important mechanism for plant tolerance and adaptation to low Mn.