Comparative metabolomics reveal key pathways associated with the synergistic activities of aztreonam and clavulanate combination against multidrug-resistant <i>Escherichia coli</i>.

Zhang, Jiayuan; Yang, Hai; Zhang, Lei; Lv, Zhihua; Yu, Mingming; Sy, Sherwin K B; Zhan, Yuanchao

Comparative metabolomics reveal key pathways associated with the synergistic activities of aztreonam and clavulanate combination against multidrug-resistant Escherichia coli.

Zhang, Jiayuan; Yang, Hai; Zhang, Lei; Lv, Zhihua; Yu, Mingming; Sy, Sherwin K B; Zhan, Yuanchao.

Afiliación

Zhang J; Ocean University of China, Qingdao, China.
Yang H; Department of Pharmacy, Affiliated Qingdao Central Hospital of Qingdao University, Qingdao Cancer Hospital, Qingdao, China.
Zhang L; Department of Laboratory Medicine, Affiliated Qingdao Central Hospital of Qingdao University, Qingdao, China.
Lv Z; Ocean University of China, Qingdao, China.
Yu M; Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.
Sy SKB; Ocean University of China, Qingdao, China.
Zhan Y; Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.

mSystems ; 8(6): e0075823, 2023 Dec 21.

Article en En | MEDLINE | ID: mdl-37830827

Asunto(s)

Aztreonam; Escherichia coli; Humanos; Aztreonam/farmacología; Escherichia coli/metabolismo; Ácido Clavulánico/farmacología; Combinación Amoxicilina-Clavulanato de Potasio/metabolismo; beta-Lactamasas/metabolismo

Palabras clave

Escherichia coli; aztreonam; clavulanate; metabolomics; synergy

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Aztreonam / Escherichia coli Límite: Humans Idioma: En Revista: MSystems Año: 2023 Tipo del documento: Article País de afiliación: China

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