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Local Control Following Stereotactic Body Radiation Therapy for Liver Oligometastases: Lessons from a Quarter Century.
Mheid, Sara; Allen, Stefan; Ng, Sylvia S W; Hall, William A; Sanford, Nina N; Aguilera, Todd A; Elamir, Ahmed M; Bahij, Rana; Intven, Martijn P W; Radhakrishna, Ganesh; Mohamad, Issa; De Leon, Jeremy; Tan, Hendrick; Lewis, Shirley; Gani, Cihan; Stanecu, Teo; Dell'Acqua, Veronica; Hosni, Ali.
Afiliación
  • Mheid S; Department of Radiation Oncology, University of Toronto, Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada.
  • Allen S; Department of Radiation Oncology, Dalhousie University, Nova Scotia Health, Halifax, NS B3H 4R2, Canada.
  • Ng SSW; Department of Radiation Oncology, University of Toronto, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
  • Hall WA; Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
  • Sanford NN; Department of Radiation Oncology, University of Texas Southwestern, Dallas, TX 75235, USA.
  • Aguilera TA; Department of Radiation Oncology, University of Texas Southwestern, Dallas, TX 75235, USA.
  • Elamir AM; Department of Radiation Oncology, University of Texas Southwestern, Dallas, TX 75235, USA.
  • Bahij R; Department of Oncology, Odense University Hospital, 5000 Odense, Denmark.
  • Intven MPW; Department of Radiotherapy, Division Imaging and Oncology, University Medical Centre, 3584 CX Utrecht, The Netherlands.
  • Radhakrishna G; Department of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX, UK.
  • Mohamad I; Department of Radiation Oncology, King Hussein Cancer Center, Amman 11941, Jordan.
  • De Leon J; GenesisCare, Alexandria, NSW 2015, Australia.
  • Tan H; Department of Radiation Oncology, Fiona Stanley Hospital, Perth, WA 6150, Australia.
  • Lewis S; GenesisCare, Perth, WA 6150, Australia.
  • Gani C; Department of Radiotherapy and Oncology, Manipal Comprehensive Cancer Care Centre, Kasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, India.
  • Stanecu T; Department of Radiation Oncology, University Hospital Tübingen, 72076 Tübingen, Germany.
  • Dell'Acqua V; Department of Radiation Oncology, University of Toronto, Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada.
  • Hosni A; Medical Affairs and Clinical Research, Linac-Based RT, Elekta Milan, 20864 Lombardy, Italy.
Curr Oncol ; 30(10): 9230-9243, 2023 10 19.
Article en En | MEDLINE | ID: mdl-37887567
ABSTRACT
The utilization of stereotactic body radiation therapy for the treatment of liver metastasis has been widely studied and has demonstrated favorable local control outcomes. However, several predictive factors play a crucial role in the efficacy of stereotactic body radiation therapy, such as the number and size (volume) of metastatic liver lesions, the primary tumor site (histology), molecular biomarkers (e.g., KRAS and TP53 mutation), the use of systemic therapy prior to SBRT, the radiation dose, and the use of advanced technology and organ motion management during SBRT. These prognostic factors need to be considered when clinical trials are designed to evaluate the efficacy of SBRT for liver metastases.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Radiocirugia / Neoplasias Hepáticas Límite: Humans Idioma: En Revista: Curr Oncol Año: 2023 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Radiocirugia / Neoplasias Hepáticas Límite: Humans Idioma: En Revista: Curr Oncol Año: 2023 Tipo del documento: Article País de afiliación: Canadá