Designing Cell Delivery Peptides and SARS-CoV-2-Targeting Small Interfering RNAs: A Comprehensive Bioinformatics Study with Generative Adversarial Network-Based Peptide Design and <i>In Vitro</i> Assays.

González, Ricardo D; Simões, Susana; Ferreira, Lino; Carvalho, Alexandra T P

Designing Cell Delivery Peptides and SARS-CoV-2-Targeting Small Interfering RNAs: A Comprehensive Bioinformatics Study with Generative Adversarial Network-Based Peptide Design and In Vitro Assays.

González, Ricardo D; Simões, Susana; Ferreira, Lino; Carvalho, Alexandra T P.

Afiliación

González RD; CNC-UC - Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Simões S; CIBB - Center for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.
Ferreira L; Institute for Interdisciplinary Research, Doctoral Programme in Experimental Biology and Biomedicine (PDBEB), University of Coimbra, 3030-789 Coimbra, Portugal.
Carvalho ATP; CNC-UC - Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.

Mol Pharm ; 20(12): 6079-6089, 2023 Dec 04.

Article en En | MEDLINE | ID: mdl-37941379

Asunto(s)

COVID-19; SARS-CoV-2; Humanos; ARN Interferente Pequeño/genética; SARS-CoV-2/genética; Células HeLa; Péptidos/metabolismo

Palabras clave

SARS-CoV-2; data analysis; databases; deep learning; delivery peptides; siRNAs

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Límite: Humans Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Portugal

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