Juvenile Idiopathic Arthritis.
Indian J Pediatr
; 91(9): 949-958, 2024 Sep.
Article
en En
| MEDLINE
| ID: mdl-38163829
ABSTRACT
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. The International League of Associations for Rheumatology (ILAR) has defined JIA as "arthritis of unknown etiology persisting for ≥6 wk with an onset at <16 y of age, after excluding other causes of joint inflammation". Synovial inflammation is the result of a complex interplay of aberrant immune systems (both adaptive and innate) in a genetically susceptible individual, with possible external stimuli/triggers. Diagnosis of JIA essentially remains clinical, and laboratory investigations usually help to assess the severity of disease activity. Few investigations like antinuclear antibodies (ANA), human leukocyte antigen (HLA)-B27, and rheumatoid factor (RF) help to categorize or prognosticate a child with JIA. Timely use of effective therapeutic interventions including biological has shown good long-term outcomes of JIA.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Artritis Juvenil
Tipo de estudio:
Prognostic_studies
Límite:
Child
/
Humans
Idioma:
En
Revista:
Indian J Pediatr
Año:
2024
Tipo del documento:
Article
País de afiliación:
India