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A Tricyclic Aromatic Polyketide Isolated from the Marine-Derived Fungus Curvularia aeria.
Kamauchi, Hitoshi; Tanaka, Mayu; Suzuki, Mitsuaki; Furukawa, Miho; Ikeda, Atsushi; Sasho, Chihiro; Kiba, Yuka; Kitamura, Masashi; Takao, Koichi; Sugita, Yoshiaki.
Afiliación
  • Kamauchi H; Department of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.
  • Tanaka M; Department of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.
  • Suzuki M; Department of Chemistry, Faculty of Science, Josai University.
  • Furukawa M; Department of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.
  • Ikeda A; Department of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.
  • Sasho C; Department of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.
  • Kiba Y; School of Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.
  • Kitamura M; School of Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.
  • Takao K; Department of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.
  • Sugita Y; Department of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.
Chem Pharm Bull (Tokyo) ; 72(1): 98-101, 2024.
Article en En | MEDLINE | ID: mdl-38233138
ABSTRACT
A novel tricyclic polyketide, curvulanone (1), was isolated from the marine-derived fungus Curvularia aeria. The structure of 1 was determined by NMR and single-crystal X-ray crystallography. 1 had a cyclopentabenzopyranone with 3-acetic acid structure that is rarely found in natural compounds. Monoamine oxidase and sirtuin 1 inhibitory test was exhibited and 1 showed their inhibitory activity.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Policétidos Idioma: En Revista: Chem Pharm Bull (Tokyo) Año: 2024 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Policétidos Idioma: En Revista: Chem Pharm Bull (Tokyo) Año: 2024 Tipo del documento: Article