Association of cardiometabolic comorbidities with mortality among low-income Black and White Americans.
J Natl Med Assoc
; 116(2 Pt 1): 189-201, 2024 Apr.
Article
en En
| MEDLINE
| ID: mdl-38296693
ABSTRACT
METHODS:
Investigated the association of multiple cardiometabolic comorbidities with total/major cause-specific mortality and evaluate if this association might be modified by race among predominantly low-income Black and White participants.METHODS:
The Southern Community Cohort Study, prospective cohort study. Participants (40-79 years) recruited predominantly from community health centers across 12 states in southeastern United States. Enrollment began in 2002 and concluded in 2009, follow-up until 2020. Cardiometabolic comorbidities (diabetes, hypertension, myocardial infarction, stroke) ascertained at the baseline survey. Cox proportional hazard models used.RESULTS:
Study included 76,721 participants; 16,197, 41,944, 5,247, and 4,919 participants with prior diagnosis of diabetes, hypertension, myocardial infarction, and stroke, respectively at baseline. Compared to individuals with no comorbidity, individuals with any single comorbidity experienced a significantly 30 to 90% increased rate of death due to any causes. The increase in mortality was elevated with an increasing number of comorbidities, with HR of 3.81 (95% CI 3.26-4.46) and a cumulative risk of 62.5% at age 75 years for total mortality for those with four comorbidities. The risk was high for death due to cardiovascular diseases (HR 6.18, 95% CI 5.12-7.47). These associations were stronger among Blacks than Whites. Individuals with four comorbidities at age 40 years were estimated to have a 16-year loss in life expectancy compared with those without any comorbidity.CONCLUSION:
Cardiometabolic comorbidities were associated with increases in all-cause and major cause-specific mortality, particularly Black Americans. This study calls for effective measures to prevent cardiometabolic comorbidities to reduce premature deaths in underserved Americans.Palabras clave
Texto completo:
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Base de datos:
MEDLINE
Asunto principal:
Accidente Cerebrovascular
/
Diabetes Mellitus
/
Hipertensión
/
Infarto del Miocardio
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
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Aged
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Humans
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Middle aged
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Natl Med Assoc
Año:
2024
Tipo del documento:
Article