Your browser doesn't support javascript.
loading
The Absorb GT1 Bioresorbable Vascular Scaffold System - 5-Year Post-Market Surveillance Study in Japan.
Nakamura, Masato; Suzuki, Nobuaki; Fujii, Kenshi; Furuya, Jungo; Kawasaki, Tomohiro; Kimura, Takumi; Sakamoto, Tomohiro; Tanabe, Kengo; Kusano, Hajime; Stockelman, Kelly A; Kozuma, Ken.
Afiliación
  • Nakamura M; Division of Minimally Invasive Treatment in Cardiovascular Medicine, Toho University Ohashi Medical Center.
  • Suzuki N; Fourth Department of Internal Medicine, Teikyo University School of Medicine.
  • Fujii K; Department of Cardiovascular Medicine, Sakurabashi Watanabe Hospital.
  • Furuya J; Department of Cardiovascular Medicine, Hanaoka Seishu Memorial Hospital.
  • Kawasaki T; Department of Cardiovascular Medicine, Shin Koga Hospital.
  • Kimura T; Department of Cardiovascular Medicine, Iwate Medical University Hospital.
  • Sakamoto T; Department of Cardiovascular Medicine, Saiseikai Kumanoto Hospital.
  • Tanabe K; Division of Cardiology, Mitsui Memorial Hospital.
  • Kusano H; Abbott Vascular.
  • Stockelman KA; Abbott Vascular.
  • Kozuma K; Department of Cardiovascular Medicine, Teikyo University Hospital.
Circ J ; 88(6): 863-872, 2024 05 24.
Article en En | MEDLINE | ID: mdl-38479861
ABSTRACT

BACKGROUND:

The 1-year clinical outcomes of the Absorb GT1 Japan post-market surveillance (PMS) suggested that an appropriate intracoronary imaging-guided bioresorbable vascular scaffold (BVS) implantation technique may reduce the risk of target lesion failure (TLF) and scaffold thrombosis (ST) associated with the Absorb GT1 BVS. The long-term outcomes through 5 years are now available. METHODS AND 

RESULTS:

This study enrolled 135 consecutive patients (n=139 lesions) with ischemic heart disease in whom percutaneous coronary intervention (PCI) with the Absorb GT1 BVS was attempted. Adequate lesion preparation, imaging-guided appropriate sizing, and high-pressure post-dilatation using a non-compliant balloon were strongly encouraged. All patients had at least 1 Absorb GT1 successfully implanted at the index procedure. Intracoronary imaging was performed in all patients (optical coherence tomography 127/139 [91.4%] lesions) and adherence to the implantation technique recommendations was excellent predilatation, 100% (139/139) lesions; post-dilatation, 98.6% (137/139) lesions; mean (±SD) post-dilatation pressure, 18.8±3.5 atm. At 5 years, the follow-up rate was 87.4% (118/135). No definite/probable ST was reported through 5 years. The cumulative TLF rate was 5.1% (6/118), including 2 cardiac deaths, 1 target vessel-attributable myocardial infarction, and 3 ischemia-driven target lesion revascularizations.

CONCLUSIONS:

Appropriate intracoronary imaging-guided BVS implantation, including the proactive use of pre- and post-balloon dilatation during implantation may be beneficial, reducing the risk of TLF and ST through 5 years.
Asunto(s)
Palabras clave

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Vigilancia de Productos Comercializados / Implantes Absorbibles Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Circ J Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2024 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Vigilancia de Productos Comercializados / Implantes Absorbibles Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Circ J Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2024 Tipo del documento: Article