Towards tailoring hydrophobic interaction with uranyl(VI) oxygen for C-H activation.

Tsushima, Satoru; Kretzschmar, Jérôme; Doi, Hideo; Okuwaki, Koji; Kaneko, Masashi; Mochizuki, Yuji; Takao, Koichiro

Tsushima, Satoru; Kretzschmar, Jérôme; Doi, Hideo; Okuwaki, Koji; Kaneko, Masashi; Mochizuki, Yuji; Takao, Koichiro.

Afiliación

Tsushima S; Institute of Resource Ecology, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, 01328, Germany. s.tsushima@hzdr.de.
Kretzschmar J; International Research Frontiers Initiative (IRFI), Institute of Innovative Research, Tokyo Institute of Technology, Tokyo, 152-8550, Japan.
Doi H; Institute of Resource Ecology, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, 01328, Germany. s.tsushima@hzdr.de.
Okuwaki K; Department of Chemistry and Research Center for Smart Molecules, Rikkyo University, Tokyo, 171-8501, Japan.
Kaneko M; Department of Chemistry and Research Center for Smart Molecules, Rikkyo University, Tokyo, 171-8501, Japan.
Mochizuki Y; Department of Chemistry, Osaka University, Osaka, 560-0043, Japan.
Takao K; Department of Chemistry, Osaka University, Osaka, 560-0043, Japan.

Chem Commun (Camb) ; 60(36): 4769-4772, 2024 Apr 30.

Article en En | MEDLINE | ID: mdl-38563824

ABSTRACT

ABSTRACT

Bovine serum albumin (BSA) has a uranyl(VI) binding hotspot where uranium is tightly bound by three carboxylates. Uranyl oxygen is "soaked" into the hydrophobic core of BSA. Isopropyl hydrogen of Val is trapped near UO22+ and upon photoexcitation, C-H bond cleavage is initiated. A unique hydrophobic contact with "yl"-oxygen, as observed here, can be used to induce C-H activation.

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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Alemania

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