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Denosumab and sclerotherapy for recurrent spinal aneurysmal bone cyst in a child.
Singh, Raj; Madasswery, Sreekumar; Colman, Matt; Kent, Paul McKeegan.
Afiliación
  • Singh R; College of Medicine, Rush University Medical Center, Chicago, Illinois, USA.
  • Madasswery S; Rush University Rush Medical College, Chicago, Illinois, USA.
  • Colman M; Rush University Rush Medical College, Chicago, Illinois, USA.
  • Kent PM; Medical Director, FibroFighters Foundation LLC, Temecula, California, USA paulkentmd@fibrofighters.org.
BMJ Case Rep ; 17(4)2024 Apr 08.
Article en En | MEDLINE | ID: mdl-38589235
ABSTRACT
Aneurysmal bone cyst (ABC) is a non-malignant, locally destructive, blood-filled lesion in the bone that tends to grow aggressively. A young girl presented with a rapid recurrence after aggressive surgery of a large symptomatic sacral-spinal ABC. After a multidisciplinary tumour board, she was successfully treated with sclerotherapy and monthly intravenous denosumab. The patient has maintained asymptomatic for over 36 months now and has returned to full activity and strength. She never required surgery and has had radiologic resolution of the lesions. Treatment of recurrent ABC requires a multidisciplinary team approach. We believe this to be the first report to use this combined therapy to provide an alternative to morbid surgery for children with ABCs.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Quistes Óseos Aneurismáticos / Denosumab Límite: Child / Female / Humans Idioma: En Revista: BMJ Case Rep Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Quistes Óseos Aneurismáticos / Denosumab Límite: Child / Female / Humans Idioma: En Revista: BMJ Case Rep Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos