The influence of age, period, and cohort factors on the incidence of kidney cancer in Spain 1990-2019: Evidence from the global burden of disease study.
Actas Urol Esp (Engl Ed)
; 48(7): 538-544, 2024 Sep.
Article
en En, Es
| MEDLINE
| ID: mdl-38599570
ABSTRACT
OBJECTIVE:
This study aimed to assess the influence of age, period, and cohort (A-P-C) factors on kidney cancer (KC) incidence trends in Spain from 1990 to 2019.METHODS:
Employing data from the Global Burden of Disease Study 2019, we employed joinpoint analysis to determine long-term patterns and A-P-C modelling to quantify net drift, local drift, longitudinal age curves, and rate ratios (RRs) of period and cohort effects.RESULTS:
Over the period 1990-2019, an estimated 142,811 cases of KC were diagnosed in Spain. A consistent upward trend in KC incidence was observed for both men and women, with the male-to-female ratio remaining stable at 2.6. Joinpoint analysis identified three distinct periods for men An initial period (1990-1995) characterised by a significant increase in rates, a subsequent period (1995-2016) characterised by a slowdown in the rate of increase, and a final period (2016-2019) in which rates have plateaued. In women, 2 time periods were observed an initial period (1990-2007) in which rates increased significantly, followed by a period of stabilization (2007-2019). Men born in the early-mid 20th century had a rising KC risk, peaking in the 1960s. Women's risk rose steadily, peaking in the late 1990s.CONCLUSION:
A-P-C analysis reveals steady KC incidence increase in both genders over three decades. This highlights the need for targeted public health policies and effective prevention strategies.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Carga Global de Enfermedades
/
Neoplasias Renales
Límite:
Adult
/
Aged
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Aged80
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Female
/
Humans
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Male
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Middle aged
País/Región como asunto:
Europa
Idioma:
En
/
Es
Revista:
Actas Urol Esp (Engl Ed)
Año:
2024
Tipo del documento:
Article
País de afiliación:
España