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Tragacanth gum-based copper oxide nanoparticles: Comprehensive characterization, antibiofilm, antimicrobial and photocatalytic potentials.
Ihsan, Sumayyah; Munir, Hira; Meng, Zihui; Tayyab, Muhammad; Zeeshan, Nadia; Rehman, Ajwa; Nadeem, Sawaira; Irfan, Muhammad.
Afiliación
  • Ihsan S; Department of Biochemistry and Biotechnology, University of Gujrat, Gujrat 50700, Pakistan.
  • Munir H; Department of Biochemistry, Government College Women University Faisalabad, Faisalabad, Pakistan.
  • Meng Z; School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 102488, China.
  • Tayyab M; Institute of Materials Research, Tsinghua Shenzhen International Graduate School (SIGS), Tsinghua University, Shenzhen 518055, China.
  • Zeeshan N; Department of Biochemistry and Biotechnology, University of Gujrat, Gujrat 50700, Pakistan.
  • Rehman A; Department of Biochemistry, Government College Women University Faisalabad, Faisalabad, Pakistan.
  • Nadeem S; Department of Biochemistry, Government College Women University Faisalabad, Faisalabad, Pakistan.
  • Irfan M; Department of Biochemistry and Biotechnology, University of Gujrat, Gujrat 50700, Pakistan. Electronic address: muhammad.irfan@uog.edu.pk.
Int J Biol Macromol ; 268(Pt 1): 131600, 2024 May.
Article en En | MEDLINE | ID: mdl-38631575
ABSTRACT
Hereunder, we pioneered the synthesis of Copper Oxide nanoparticles (CuO NPs) utilizing Tragacanth gum (TG). The NPs were characterized using advanced techniques and assessed for different pharmaceutical and environmental perspectives. The successful formation of a colloidal NPs solution was confirmed by the appearance of a distinct black color and a distinct peak at 260 nm in UV-Visible spectrophotometry. The FTIR analysis unveiled a spectrum of functional groups responsible for the reduction and stabilization of CuO NPs. Dynamic Light Scattering (DLS) and Transmission Electron Microscopy (TEM) revealed size of NPs as 36.24 nm and 28 ± 04 nm respectively. Energy Dispersive X-ray (EDX) Analysis indicated weight percentages of 70.38 % for Cu and 18.88 % for O, with corresponding atomic percentages. The X-ray Diffraction (XRD) analysis revealed the orthorhombic crystal structure of the prepared CuO NPs. Antimicrobial assessments through disc-diffusion assays demonstrated significant zones of inhibition (ZOI) against gram-positive bacterial strains (Bacillus Halodurans and Micrococcus leutus) and a gram-negative bacterial strain (E. coli). Against the fungal strain Aspergillus niger, a ZOI of 18.5 ± 0.31 mm was observed. The NPs exhibited remarkable antioxidant potential determined through 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and H2O2 scavenging assays. At a concentration of 3 mg/mL, the NPs demonstrated biofilm inhibition rates of 96 %, 90 %, 89.60 %, and 72.10 % against Micrococcus luteus, Bacillus halodurans, MRSA and E.coli respectively. Furthermore, the CuO NPs showed a high photocatalytic potential towards the degradation of safranin dye under sunlight irradiation. In conclusion, the findings underline the promising multifunctional properties of TG-based CuO NPs for different practical applications.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tragacanto / Biopelículas / Cobre / Nanopartículas del Metal Idioma: En Revista: Int J Biol Macromol Año: 2024 Tipo del documento: Article País de afiliación: Pakistán

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tragacanto / Biopelículas / Cobre / Nanopartículas del Metal Idioma: En Revista: Int J Biol Macromol Año: 2024 Tipo del documento: Article País de afiliación: Pakistán