Potential for targeting small heat shock protein modifications.
Trends Pharmacol Sci
; 45(7): 583-585, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-38704305
ABSTRACT
Small heat shock proteins (sHSPs) play key roles in cellular stress and several human diseases. The direct effects of some post-translational modifications (PTMs) on certain sHSPs have been characterized, raising the possibility that small molecules could be used to modulate these modifications and indirectly up- or downregulate sHSP activity.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Procesamiento Proteico-Postraduccional
/
Proteínas de Choque Térmico Pequeñas
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Pharmacol Sci
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos