A green, facile, and practical preparation of capsaicin derivatives with thiourea structure.
Sci Rep
; 14(1): 10576, 2024 05 08.
Article
en En
| MEDLINE
| ID: mdl-38719947
ABSTRACT
Capsaicin derivatives with thiourea structure (CDTS) is highly noteworthy owing to its higher analgesic potency in rodent models and higher agonism in vitro. However, the direct synthesis of CDTS remains t one or more shortcomings. In this study, we present reported a green, facile, and practical synthetic method of capsaicin derivatives with thiourea structure is developed by using an automated synthetic system, leading to a series of capsaicin derivatives with various electronic properties and functionalities in good to excellent yields.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Tiourea
/
Capsaicina
Límite:
Animals
Idioma:
En
Revista:
Sci Rep
Año:
2024
Tipo del documento:
Article