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A novel target to turn cold tumors into hot tumors: lysosomal 25-hydroxycholesterol activates AMPKα and immunosuppressive tumor-associated macrophages.
Liu, Shuangshuang; Wu, Jiaqi; Tong, Xiao; Huang, Li-Hao.
Afiliación
  • Liu S; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
  • Wu J; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
  • Tong X; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
  • Huang LH; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. lihao_huang@fudan.edu.cn.
Cell Mol Immunol ; 21(8): 801-803, 2024 Aug.
Article en En | MEDLINE | ID: mdl-38740924
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Quinasas Activadas por AMP / Macrófagos Asociados a Tumores / Hidroxicolesteroles / Lisosomas Límite: Animals / Humans Idioma: En Revista: Cell Mol Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Quinasas Activadas por AMP / Macrófagos Asociados a Tumores / Hidroxicolesteroles / Lisosomas Límite: Animals / Humans Idioma: En Revista: Cell Mol Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China