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[Research hotspots and frontiers of Realgar based on CiteSpace knowledge graph analysis].
Wu, Feng-Zhen; Wang, Ming-Jing; Lyu, Yan; Fu, Jian-Hua; Hu, Xiao-Mei.
Afiliación
  • Wu FZ; Post-doctoral Scientific Research Station, China Academy of Chinese Medical Sciences Beijing 100700, China Department of Hematology, Xiyuan Hospital, China Academy of Chinese Medical Sciences Beijing 100091, China.
  • Wang MJ; Department of Hematology, Xiyuan Hospital, China Academy of Chinese Medical Sciences Beijing 100091, China.
  • Lyu Y; Department of Hematology, Xiyuan Hospital, China Academy of Chinese Medical Sciences Beijing 100091, China.
  • Fu JH; Institute of Basic Medicine, Xiyuan Hospital, China Academy of Chinese Medical Sciences Beijing 100091, China National Clinical Research Center for Chinese Medicine Cardiology Beijing 100091, China.
  • Hu XM; Department of Hematology, Xiyuan Hospital, China Academy of Chinese Medical Sciences Beijing 100091, China.
Zhongguo Zhong Yao Za Zhi ; 49(9): 2532-2543, 2024 May.
Article en Zh | MEDLINE | ID: mdl-38812149
ABSTRACT
This study employed knowledge graph technology to analyze the research status and hot spots of Realgar and provide guidance for clinical application and further research of this drug. The research articles both in English and Chinese involving Realgar were retrieved from five databases including CNKI, Wanfang, VIP, SinoMed, and Web of Science. And NoteExpress, a literature management software was used to screen literature. CiteSpace was utilized for visualized analysis and presentations of the authors, institutions, and keywords. 2 879 articles in Chinese and 194 articles in English were included. China Journal of Chinese Materia Medica and Journal of Ethnopharmacology were the top Chinese and English journals in terms of publication volume. Realgar is widely used in the treatment of skin diseases, blood diseases, and cancer. JIANG Hong was the author who have published more articles in Chinese and English working with teams. School of Public Health of China Medical University and China Academy of Chinese Medical Sciences published the most articles in Chinese and English. The research on Realgar mainly focuses on clinical application, mechanism of action, reduction of toxicity, and enhancement of efficacy. The authors and institutions of Realgar research are mainly concentrated in China. The study on the mechanism of treating hematological diseases and cancer with Realgar, as well as the research on its effects of reducing toxicity and enhancing efficacy, are the current research hotspots. The mechanism of "same treatment for different diseases" in Realgar needs to be further explored. It is urgent to carry out interdisciplinary research on Realgar. This study can provide a refe-rence for the clinical application of Realgar and provide ideas for further research on Realgar.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Arsenicales / Sulfuros Límite: Humans País/Región como asunto: Asia Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Asunto de la revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Año: 2024 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Arsenicales / Sulfuros Límite: Humans País/Región como asunto: Asia Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Asunto de la revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Año: 2024 Tipo del documento: Article País de afiliación: China