A mild deprotection of isopropylidene ketals from 2-deoxyglycosides using AcOH/H2O/DME: An efï¬cient regioselective deprotection of terminal isopropylidene ketals.
Carbohydr Res
; 541: 109167, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-38823063
ABSTRACT
This paper describes a mild and efficient catalytic deprotection method for isopropylidene ketals and benzylidene acetals using AcOH/H2O/DME(1,2-Dimethoxyethane). The method effectively removes ketal and acetal protecting groups from 2-deoxyglycosides which are prone to hydrolysis under acidic conditions. Moreover, it enables the selective removal of the terminal ketal over an internal one.
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Base de datos:
MEDLINE
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Glicósidos
Idioma:
En
Revista:
Carbohydr Res
Año:
2024
Tipo del documento:
Article
País de afiliación:
China