Gut microbial ß-Glucuronidase: A key regulator of endobiotic homeostasis.

Ning, Lijun; Hong, Jie

Ning, Lijun; Hong, Jie.

Afiliación

Ning L; State Key Laboratory of Systems Medicine for Cancer, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Shanghai 200001, China.
Hong J; State Key Laboratory of Systems Medicine for Cancer, NHC Key Laboratory of Digestive Diseases, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai Cancer Institute, Shanghai 200001, China. Electronic address: jiehong97@sjtu.edu.cn.

Cell Host Microbe ; 32(6): 783-785, 2024 Jun 12.

Article en En | MEDLINE | ID: mdl-38870895

ABSTRACT

ABSTRACT

Previous studies have explored the role of the gut microbiota in regulating endobiotic homeostasis, but the precise mechanisms remain unclear. In this issue of Cell Host & Microbe, Simpson et al. identified two predominant subtypes of gut microbial ß-Glucuronidase (gmGUS) that can reactivate hormones and neurotransmitters to regulate endobiotic homeostasis.

Asunto(s)

Microbioma Gastrointestinal; Glucuronidasa; Homeostasis; Glucuronidasa/metabolismo; Glucuronidasa/genética; Microbioma Gastrointestinal/fisiología; Humanos; Animales; Tracto Gastrointestinal/microbiología; Bacterias/enzimología; Bacterias/metabolismo; Bacterias/genética

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Microbioma Gastrointestinal / Glucuronidasa / Homeostasis Límite: Animals / Humans Idioma: En Revista: Cell Host Microbe Asunto de la revista: MICROBIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China

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