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The Effect of Etrasimod on Fecal Calprotectin and High-sensitivity C-reactive Protein: Results From the ELEVATE UC Clinical Program.
Jairath, Vipul; Rubin, David T; Verstockt, Bram; Çekin, Ayhan H; Abreu, Maria T; Lees, Charlie W; Fellmann, Marc; Woolcott, John C; Crosby, Catherine; Wu, Joseph; Bhattacharjee, Abhishek; Herman, David; Gu, Guibao; Siegmund, Britta.
Afiliación
  • Jairath V; Department of Medicine and Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
  • Rubin DT; University of Chicago Medicine Inflammatory Bowel Disease Center, Chicago, IL, USA.
  • Verstockt B; Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
  • Çekin AH; Department of Chronic Diseases and Metabolism, Translational Research in Gastrointestinal Disorders, KU Leuven, Leuven, Belgium.
  • Abreu MT; Department of Gastroenterology, University of Health Sciences, Antalya Training and Research Hospital, Antalya, Turkey.
  • Lees CW; Division of Gastroenterology, Crohn's and Colitis Center, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Fellmann M; The Edinburgh Inflammatory Bowel Disease Unit, Western General Hospital, Edinburgh, Scotland, UK.
  • Woolcott JC; Pfizer AG, Zürich, Switzerland.
  • Crosby C; Pfizer Inc, Collegeville, PA, USA.
  • Wu J; Pfizer Inc, La Jolla, CA, USA.
  • Bhattacharjee A; Pfizer Inc, Cambridge, MA, USA.
  • Herman D; Pfizer Healthcare India Pvt Ltd, Chennai, Tamil Nadu, India.
  • Gu G; Pfizer Inc, La Jolla, CA, USA.
  • Siegmund B; Pfizer Inc, La Jolla, CA, USA.
Inflamm Bowel Dis ; 2024 Jun 20.
Article en En | MEDLINE | ID: mdl-38899786
We show associations between fecal calprotectin (fCAL) and high-sensitivity C-reactive protein (hsCRP) levels with efficacy outcomes among patients receiving 2 mg of etrasimod once daily, and that fCAL levels may be an early indicator of the achievement of long-term efficacy end point achievement.
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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Inflamm Bowel Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Inflamm Bowel Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Canadá