Recombination of variable and host range regions of glycoprotein gp85 in different avian leukosis virus subgroup K isolates.
Arch Virol
; 169(7): 155, 2024 Jun 29.
Article
en En
| MEDLINE
| ID: mdl-38951272
ABSTRACT
Given the high prevalence of avian leukosis virus subgroup K (ALV-K) in chickens in China, the positive rate of ALV-K in local chickens in Henan province was investigated, and the genetic region encoding the glycoprotein gp85 of isolates from positive chickens was analyzed. The positive rate of ALV-K in local chickens in Henan was found to be 87.2% (41/47). Phylogenetic analysis of gp85 sequences revealed six clusters that differed in their host range regions (hr1 and hr2) and variable regions (vr1, vr2, and vr3). Evidence of recombination of hr1, hr2, vr1, vr2, and vr3 was observed between the different clusters. The isolate HN23LS02 appears to have obtained its hr1 and hr2 regions from separate lineages via recombination but without having a significant affect on the replication capacity of the virus.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Filogenia
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Enfermedades de las Aves de Corral
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Recombinación Genética
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Leucosis Aviar
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Pollos
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Proteínas del Envoltorio Viral
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Virus de la Leucosis Aviar
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Especificidad del Huésped
Límite:
Animals
País/Región como asunto:
Asia
Idioma:
En
Revista:
Arch Virol
Año:
2024
Tipo del documento:
Article
País de afiliación:
China