Tepotinib in a Patient With Advanced Non-Small Cell Lung Cancer Harboring MET Exon 14 Skipping Undergoing Concomitant Hemodialysis for Renal Failure: A Case Report.

Kleemiss, Moritz; Müller, Christa E; Schneider, Marion; Strotmann, Rainer; Orlowski, Katrin; Goteti, Kosalaram; Yanik, Mert; Brossart, Peter; Bauernfeind, Franz-Georg

Kleemiss, Moritz; Müller, Christa E; Schneider, Marion; Strotmann, Rainer; Orlowski, Katrin; Goteti, Kosalaram; Yanik, Mert; Brossart, Peter; Bauernfeind, Franz-Georg.

Afiliación

Kleemiss M; Department of internal Medicine III, University Hospital Bonn, Bonn, Germany. Electronic address: moritz.kleemiss@ukbonn.de.
Müller CE; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn.
Schneider M; PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn.
Strotmann R; Qualitative Pharmacology, the healthcare business of Merck KGaA, Darmstadt, Germany.
Orlowski K; Merck Healthcare Germany GmbH, Weiterstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany.
Goteti K; Quantitative Pharmacology, EMD Serono, Rockland, MA.
Yanik M; Merck Healthcare Germany GmbH, Weiterstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany.
Brossart P; Department of internal Medicine III, University Hospital Bonn, Bonn, Germany.
Bauernfeind FG; Department of internal Medicine III, University Hospital Bonn, Bonn, Germany.

Clin Lung Cancer ; 25(6): 577-580, 2024 Sep.

Article en En | MEDLINE | ID: mdl-38987049

Asunto(s)

Carcinoma de Pulmón de Células no Pequeñas; Exones; Neoplasias Pulmonares; Proteínas Proto-Oncogénicas c-met; Pirimidinas; Diálisis Renal; Humanos; Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico; Carcinoma de Pulmón de Células no Pequeñas/genética; Carcinoma de Pulmón de Células no Pequeñas/complicaciones; Carcinoma de Pulmón de Células no Pequeñas/patología; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/tratamiento farmacológico; Neoplasias Pulmonares/patología; Neoplasias Pulmonares/complicaciones; Proteínas Proto-Oncogénicas c-met/genética; Exones/genética; Pirimidinas/uso terapéutico; Masculino; Insuficiencia Renal/terapia; Piridinas/uso terapéutico; Persona de Mediana Edad; Anciano; Antineoplásicos/uso terapéutico; Piperidinas; Piridazinas

Palabras clave

End stage renal disease (ESRD); MET inhibitor; Mesenchymal-epithelial transition factor; Pharmacokinetics (PK); Severe renal impairment

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirimidinas / Exones / Diálisis Renal / Carcinoma de Pulmón de Células no Pequeñas / Proteínas Proto-Oncogénicas c-met / Neoplasias Pulmonares Límite: Aged / Humans / Male / Middle aged Idioma: En Revista: Clin Lung Cancer Asunto de la revista: NEOPLASIAS Año: 2024 Tipo del documento: Article

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