Cobalt-catalyzed Synthesis of Alkenes and Vinyl Sulfones via Dehydrogenative Coupling of Alcohols and Sulfones.
ChemSusChem
; : e202401244, 2024 Jul 17.
Article
en En
| MEDLINE
| ID: mdl-39016039
ABSTRACT
A novel protocol to access vinyl sulfones and internal/terminal olefins via cobalt-catalyzed acceptorless dehydrogenation coupling (ADC) has been established. This system enables the divergent synthesis of three kinds of olefin compounds through the coupling of alcohols and sulfones under oxidant-free conditions. The broad applicability of this procedure is demonstrated by over forty olefin products, including pharmaceutical-related compounds and complex substrates, in a one-pot process. Preliminary mechanistic studies were conducted, and a proposed reaction pathway was presented.
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Base de datos:
MEDLINE
Idioma:
En
Revista:
ChemSusChem
Asunto de la revista:
QUIMICA
/
TOXICOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
China