Long-term ultraviolet B irradiation at 297â
nm with light-emitting diode improves bone health via vitamin D regulation.
Biomed Opt Express
; 15(7): 4081-4100, 2024 Jul 01.
Article
en En
| MEDLINE
| ID: mdl-39022556
ABSTRACT
Ultraviolet radiation is the primary determinant for vitamin D synthesis. Sunlight is inefficient and poses a risk, particularly for long-term exposure. In this study, we screened the most favorable wavelength for vitamin D synthesis among four types of narrowband light-emitting diodes (LEDs) and then irradiated osteoporosis rats with the optimal wavelength for 3-12 months. The 297â
nm narrowband LED was the most efficient. Long-term radiation increased vitamin D levels in all osteoporotic rats and improved bone health. No skin damage was observed during irradiation. Our findings provide an efficient and safe method of vitamin D supplementation.
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MEDLINE
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En
Revista:
Biomed Opt Express
Año:
2024
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Article
País de afiliación:
China