Association between the systemic immune-inflammation index and obesity among adults: Insights from the NHANES 2017-2018.
PLoS One
; 19(8): e0308288, 2024.
Article
en En
| MEDLINE
| ID: mdl-39116149
ABSTRACT
BACKGROUND:
Inflammation is an important causative factor of obesity. This study aimed to explore the possible association between the systemic immune-inflammatory index, a novel indicator of inflammation, and obesity.METHODS:
Data were collected from 4395 participants of the National Health and Nutrition Examination Survey 2017-2018 aged ≥ 20 years. The systemic immune-inflammatory index was calculated by multiplying the platelet count by the neutrophil-to-lymphocyte ratio. Obesity was defined as a body mass index ≥ 30 kg/m2.RESULTS:
A significant positive correlation was observed between the systemic immune-inflammatory index and body mass index following multivariate linear regression analysis (ß = 1.75; 95% confidence interval = 1.16-2.33), which was greatest in adults aged < 60 years without hypertension and diabetes. Smoothed curve fitting and threshold effect analysis were used to characterize the nonlinear association between the systemic immune-inflammatory index and body mass index, and the inflection point was found to be 729.3.CONCLUSIONS:
The systemic immune-inflammatory index is positively associated with body mass index among adults in the United States and has the potential to enhance efforts to prevent adult obesity.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Índice de Masa Corporal
/
Encuestas Nutricionales
/
Inflamación
/
Obesidad
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
America do norte
Idioma:
En
Revista:
PLoS One
Asunto de la revista:
CIENCIA
/
MEDICINA
Año:
2024
Tipo del documento:
Article
País de afiliación:
China