Polyphenol Treatment of Peripheral Blood Mononuclear Cells from Individuals of Different Ages.
Methods Mol Biol
; 2857: 191-221, 2025.
Article
en En
| MEDLINE
| ID: mdl-39348067
ABSTRACT
Human peripheral blood mononuclear cells (PBMCs) have been largely utilized to assess the cytotoxic, immunomodulatory, and anti-inflammatory properties of both synthetic and natural compounds. Within the latter category, polyphenols from dietary sources have been extensively analyzed. PBMCs represent a feasible in vitro model to study polyphenol hallmarks and activity according to quantitative and qualitative differences in immune responses in individuals of different age. In this chapter, we propose a method for PBMC treatment with polyphenols and analysis designed on age-dependent qualitative and quantitative variability in immune cell performance.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Leucocitos Mononucleares
/
Polifenoles
Límite:
Humans
Idioma:
En
Revista:
Methods Mol Biol
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2025
Tipo del documento:
Article
País de afiliación:
Italia