A brief review of ultrasensitive prostate-specific antigen assays for the evaluation of patients after radical prostatectomy.
World J Urol
; 11(4): 192-5, 1993.
Article
en En
| MEDLINE
| ID: mdl-7508782
ABSTRACT
The development of immunoassays for prostate-specific antigen (PSA) and their clinical utility are summarized. Because of the complexity of the PSA molecule and anti-PSA antibodies, there is currently no standard in PSA measurement. Evaluating various immunoassays requires the knowledge of the lower limit of detection as well as the biological and clinical thresholds of a given assay. There have been recent reports demonstrating earlier detection of residual prostate cancer after radical prostatectomy by ultrasensitive assays for PSA. Because of the recent evidence for non-prostatic sources of PSA such as the male urethra, the possibility of their contaminating PSA levels must be evaluated when more sensitive assays for PSA are under consideration.
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Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Próstata
/
Antígeno Prostático Específico
Límite:
Humans
/
Male
Idioma:
En
Revista:
World J Urol
Año:
1993
Tipo del documento:
Article